Multiple Sclerosis (MS)
Advances in Multiple Sclerosis(MS) research
MS is an autoimmune disease in which immune cells attack and destroy the protective myelin sheaths that surround nerve fibres, leading to neurological disturbances. With the disease’s repetitive recurrence or continuous progression, resulting in central nerve axons damage and nerve necrosis, patients would present sequela conditions of central nerve necrosis, including limbs’s paralysis, balance disturbance, etc.
There is currently no cure for MS, although various treatment methods have been available to help alleviate symptoms and slow disease progression. However, for patients with frequent MS relapses, damage to the central nervous system—including demyelination, axonal neuropathy, and neuronal necrosis—is inevitable. Such damage can lead to permanent paralysis, balance disturbance, visual impairment and sensory impairment, etc.
Previous treatments mostly rely on immunosuppressive therapies (such as corticosteroids), but these come with numerous side effects, such as fever, bone and organ damage, and increased susceptibility to infections due to weakened immunity. Moreover, infections could easily trigger MS relapses, creating a paradoxical treatment dilemma.
Current research focuses on treatment methods that can not only effectively prevent MS relapse or MS progression, but also can restore the function of damaged nerves (both acute injuries and nerve injury sequelae). Besides, patient’s immune system should not get disrupted with little side effects caused. The goal is to reduce disability rates and to improve quality of life.
Through decades of research and clinical practice, Wu Medical Center(WMC) has already helped many MS patients, representing the future treatment direction.
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